In vitro Antiviral Effect of Meroditerpenes Isolated from the Brazilian Seaweed Stypopodium zonale (Dictyotales)

Abstract

The meroditerpenoids atomaric acid (1), epitaondiol (2) and the peroxylactone of 5′a-desmethyl-5′-acetylatomaric acid (3) were isolated from the Brazilian brown alga Stypopodium zonale collected in two localities (Búzios and Marataízes, RJ and ES States). These compounds showed strong anti-HSV-1 activity in vitro but neither of them inhibited the transcriptase reverse enzyme of HIV-1.

References

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