The influence of progesterone, estrogens and their antagonists: mifepristone and tamoxifen
on connective tissue metabolism in pregnant rat uterus near term was evaluated. Total
collagen and its soluble fraction as well as water concentration was measured in a
population of 65 pregnant rats; treated with progesterone (n = 10), mifepristone (n
= 13), estradiol (n = 17) and tamoxifen (n = 12). The results suggest the important
influence of sex steroids on the uterine connective tissue metabolism during pregnancy.
Uterus - Collagen - Progesterone - Mifepristone - Estradiol - Tamoxifen
