Clin Colon Rectal Surg 2007; 20(2): 102-109
DOI: 10.1055/s-2007-977488
Copyright © 2007 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Perianal Abscess/Fistula Disease

Mark H. Whiteford1 , 2
  • 1Gastrointestinal and Minimally Invasive Surgical Division, Legacy Portland Hospitals, Portland, Oregon
  • 2Oregon Health and Science University, Portland, Oregon
Further Information

Publication History

Publication Date:
09 May 2007 (online)

ABSTRACT

Perirectal abscesses and fistulas represent the acute and chronic manifestations of the same disease process, an infected anal gland. They have beleaguered patients and physicians for millennia. A thorough understanding of the anatomy and pathophysiology of the disease process is critical for optimal diagnosis and management. Abscess management is fairly straightforward, with incision and drainage being the hallmark of therapy. Fistula management is much more complicated. It requires striking a balance between rates of healing and potential alteration of fecal continence. This, therefore, requires much more finesse. Many techniques are now available in the armamentarium of the surgeon who treats fistula-in-ano. Although no single technique is appropriate for all patients and all fistula types, appropriate selection of patients and choice of repair technique should yield higher success rates with lower associated morbidity.

REFERENCES

  • 1 Parks A G. Pathogenesis and treatment of fistula-in-ano.  Br Med J. 1961;  1 463-469
  • 2 Eisenhammer S. The internal anal sphincter and the anorectal abscess.  Surg Gynecol Obstet. 1956;  103 501-506
  • 3 Whiteford M H, Kilkenny III J, Hyman N et al.. Practice parameters for the treatment of perianal abscess and fistula-in-ano (revised).  Dis Colon Rectum. 2005;  48 1337-1342
  • 4 Isbister W H. A simple method for the management of anorectal abscess.  Aust N Z J Surg. 1987;  57 771-774
  • 5 Read D R, Abcarian H. A prospective survey of 474 patients with anorectal abscess.  Dis Colon Rectum. 1979;  22 566-568
  • 6 Vasilevsky C A, Gordon P H. The incidence of recurrent abscesses or fistula-in-ano following anorectal suppuration.  Dis Colon Rectum. 1984;  27 126-130
  • 7 Llera J L, Levy R C. Treatment of cutaneous abscess: a double-blind clinical study.  Ann Emerg Med. 1985;  14 15-19
  • 8 Stewart M P, Laing M R, Krukowski Z H. Treatment of acute abscesses by incision, curettage and primary suture without antibiotics: a controlled clinical trial.  Br J Surg. 1985;  72 66-67
  • 9 Macfie J, Harvey J. The treatment of acute superficial abscesses: a prospective clinical trial.  Br J Surg. 1977;  64 264-266
  • 10 Dajani A S, Taubert K A, Wilson W et al.. Prevention of bacterial endocarditis. Recommendations by the American Heart Association.  Circulation. 1997;  96 358-366
  • 11 Tonkin D M, Murphy E, Brooke-Smith M et al.. Perianal abscess: a pilot study comparing packing with nonpacking of the abscess cavity.  Dis Colon Rectum. 2004;  47 1510-1514
  • 12 Parks A G, Gordon P H, Hardcastle J D. A classification of fistula-in-ano.  Br J Surg. 1976;  63 1-12
  • 13 Parks A G, Stitz R W. The treatment of high fistula-in-ano.  Dis Colon Rectum. 1976;  19 487-499
  • 14 Kodner I J, Mazor A, Shemesh E I, Fry R D, Fleshman J W, Birnbaum E H. Endorectal advancement flap repair of rectovaginal and other complicated anorectal fistulas.  Surgery. 1993;  114 682-689 discussion 689-690
  • 15 Mizrahi N, Wexner S D, Zmora O et al.. Endorectal advancement flap: are there predictors of failure?.  Dis Colon Rectum. 2002;  45 1616-1621
  • 16 Garcia-Aguilar J, Belmonte C, Wong W D, Goldberg S M, Madoff R D. Anal fistula surgery. Factors associated with recurrence and incontinence.  Dis Colon Rectum. 1996;  39 723-729
  • 17 van Tets W F, Kuijpers H C. Continence disorders after anal fistulotomy.  Dis Colon Rectum. 1994;  37 1194-1197
  • 18 Vasilevsky C A, Gordon P H. Results of treatment of fistula-in-ano.  Dis Colon Rectum. 1985;  28 225-231
  • 19 Ho Y H, Tan M, Leong A F, Seow-Choen F. Marsupialization of fistulotomy wounds improves healing: a randomized controlled trial.  Br J Surg. 1998;  85 105-107
  • 20 Abel M E, Chiu Y S, Russell T R, Volpe P A. Autologous fibrin glue in the treatment of rectovaginal and complex fistulas.  Dis Colon Rectum. 1993;  36 447-449
  • 21 Dietz D W. Role of fibrin glue in the management of simple and complex fistula in ano.  J Gastrointest Surg. 2006;  10 631-632
  • 22 Johnson E K, Gaw J U, Armstrong D N. Efficacy of anal fistula plug vs. fibrin glue in closure of anorectal fistulas.  Dis Colon Rectum. 2006;  49 371-376
  • 23 O'Connor L, Champagne B J, Ferguson M A, Orangio G R, Schertzer M E, Armstrong D N. Efficacy of anal fistula plug in closure of Crohn's anorectal fistulas.  Dis Colon Rectum. 2006;  49 1569-1573
  • 24 Robb B W, Nussbaum M N, Vogler S A, Sklow B. Early experience using porcine small intestinal submucosa to repair fistulas-in-ano. Annual Meeting of the American Society of Colon and Rectal Surgeons. Dallas, TX; 2004
  • 25 Champagne B J, O'Connor L M, Ferguson M, Orangio G R, Schertzer M E, Armstrong D N. Efficacy of anal fistula plug in closure of cryptoglandular fistulas: long-term follow-up.  Dis Colon Rectum. 2006;  49 1817-1821
  • 26 Poirier M, Citron J, Nelson R, Prasad L, Abcarian H. Surgisis AFP: a changing paradigm in the treatment of fistula-in-ano? Annual Meeting of the American Society of Colon and Rectal Surgeons. Seattle, WA; 2006
  • 27 Ratto C, Gentile E, Merico M et al.. How can the assessment of fistula-in-ano be improved?.  Dis Colon Rectum. 2000;  43 1375-1382
  • 28 Orsoni P, Barthet M, Portier F, Panuel M, Desjeux A, Grimaud J C. Prospective comparison of endosonography, magnetic resonance imaging and surgical findings in anorectal fistula and abscess complicating Crohn's disease.  Br J Surg. 1999;  86 360-364
  • 29 Schwartz D A, Wiersema M J, Dudiak K M et al.. A comparison of endoscopic ultrasound, magnetic resonance imaging, and exam under anesthesia for evaluation of Crohn's perianal fistulas.  Gastroenterology. 2001;  121 1064-1072
  • 30 Aguilar P S, Plasencia G, Hardy Jr T G, Hartmann R F, Stewart W R. Mucosal advancement in the treatment of anal fistula.  Dis Colon Rectum. 1985;  28 496-498
  • 31 Sonoda T, Hull T, Piedmonte M R, Fazio V W. Outcomes of primary repair of anorectal and rectovaginal fistulas using the endorectal advancement flap.  Dis Colon Rectum. 2002;  45 1622-1628
  • 32 Ozuner G, Hull T L, Cartmill J, Fazio V W. Long-term analysis of the use of transanal rectal advancement flaps for complicated anorectal/vaginal fistulas.  Dis Colon Rectum. 1996;  39 10-14
  • 33 Schouten W R, Zimmerman D D, Briel J W. Transanal advancement flap repair of transsphincteric fistulas.  Dis Colon Rectum. 1999;  42 1419-1422 discussion 1422-1413
  • 34 Ortiz H, Marzo J. Endorectal flap advancement repair and fistulectomy for high trans-sphincteric and suprasphincteric fistulas.  Br J Surg. 2000;  87 1680-1683
  • 35 Williams J G, MacLeod C A, Rothenberger D A, Goldberg S M. Seton treatment of high anal fistulae.  Br J Surg. 1991;  78 1159-1161
  • 36 Garcia-Aguilar J, Belmonte C, Wong D W, Goldberg S M, Madoff R D. Cutting seton versus two-stage seton fistulotomy in the surgical management of high anal fistula.  Br J Surg. 1998;  85 243-245
  • 37 Pearl R K, Andrews J R, Orsay C P et al.. Role of the seton in the management of anorectal fistulas.  Dis Colon Rectum. 1993;  36 573-577 discussion 577-579
  • 38 Michelassi F, Melis M, Rubin M, Hurst R D. Surgical treatment of anorectal complications in Crohn's disease.  Surgery. 2000;  128 597-603
  • 39 Faucheron J L, Saint-Marc O, Guibert L, Parc R. Long-term seton drainage for high anal fistulas in Crohn's disease-a sphincter-saving operation?.  Dis Colon Rectum. 1996;  39 208-211
  • 40 Sangwan Y P, Schoetz Jr D J, Murray J J, Roberts P L, Coller J A. Perianal Crohn's disease. Results of local surgical treatment.  Dis Colon Rectum. 1996;  39 529-535
  • 41 Williams J G, Rothenberger D A, Nemer F D, Goldberg S M. Fistula-in-ano in Crohn's disease. Results of aggressive surgical treatment.  Dis Colon Rectum. 1991;  34 378-384
  • 42 Fry R D, Shemesh E I, Kodner I J, Timmcke A. Techniques and results in the management of anal and perianal Crohn's disease.  Surg Gynecol Obstet. 1989;  168 42-48
  • 43 White R A, Eisenstat T E, Rubin R J, Salvati E P. Seton management of complex anorectal fistulas in patients with Crohn's disease.  Dis Colon Rectum. 1990;  33 587-589
  • 44 Scott H J, Northover J M. Evaluation of surgery for perianal Crohn's fistulas.  Dis Colon Rectum. 1996;  39 1039-1043
  • 45 Levien D H, Surrell J, Mazier W P. Surgical treatment of anorectal fistula in patients with Crohn's disease.  Surg Gynecol Obstet. 1989;  169 133-136
  • 46 Marks C G, Ritchie J K, Lockhart-Mummery H E. Anal fistulas in Crohn's disease.  Br J Surg. 1981;  68 525-527
  • 47 Sohn N, Korelitz B I, Weinstein M A. Anorectal Crohn's disease: definitive surgery for fistulas and recurrent abscesses.  Am J Surg. 1980;  139 394-397
  • 48 van Dongen L M, Lubbers E J. Perianal fistulas in patients with Crohn's disease.  Arch Surg. 1986;  121 1187-1190
  • 49 Loungnarath R, Dietz D W, Mutch M G, Birnbaum E H, Kodner I J, Fleshman J W. Fibrin glue treatment of complex anal fistulas has low success rate.  Dis Colon Rectum. 2004;  47 432-436
  • 50 Venkatesh K S, Ramanujam P. Fibrin glue application in the treatment of recurrent anorectal fistulas.  Dis Colon Rectum. 1999;  42 1136-1139
  • 51 Cintron J R, Park J J, Orsay C P et al.. Repair of fistulas-in-ano using fibrin adhesive: long-term follow-up.  Dis Colon Rectum. 2000;  43 944-949 discussion 949-950
  • 52 Zmora O, Mizrahi N, Rotholtz N et al.. Fibrin glue sealing in the treatment of perineal fistulas.  Dis Colon Rectum. 2003;  46 584-589
  • 53 Sentovich S M. Fibrin glue for anal fistulas: long-term results.  Dis Colon Rectum. 2003;  46 498-502
  • 54 Makowiec F, Jehle E C, Becker H D, Starlinger M. Clinical course after transanal advancement flap repair of perianal fistula in patients with Crohn's disease.  Br J Surg. 1995;  82 603-606
  • 55 Hull T L, Fazio V W. Surgical approaches to low anovaginal fistula in Crohn's disease.  Am J Surg. 1997;  173 95-98
  • 56 Jones I T, Fazio V W, Jagelman D G. The use of transanal rectal advancement flaps in the management of fistulas involving the anorectum.  Dis Colon Rectum. 1987;  30 919-923

Mark H WhitefordM.D. 

Gastrointestinal and Minimally Invasive Surgical Division, Legacy Portland Hospitals

1040 Northwest 22nd Ave., Ste. #560, Portland, OR 97210

Email: mwhiteford@orclinic.com

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