Arthrogryposis Multiplex Congenita and Bilateral Parietal Polymicrogyria in Association with the Intrauterine Death of a Twin

E. M. Baker; M. Ghazavi Khorasgani; D. Gardner-Medwin; A. Gholkar; P. D. Griffiths

doi:10.1055/s-2007-973749

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Neuropediatrics 1996; 27(1): 54-56
DOI: 10.1055/s-2007-973749

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Arthrogryposis Multiplex Congenita and Bilateral Parietal Polymicrogyria in Association with the Intrauterine Death of a Twin

E. M. Baker¹ , M. Ghazavi Khorasgani² , D. Gardner-Medwin² , A. Gholkar¹ , P. D. Griffiths¹

¹Department of Neuroradiology, Newcastle General Hospital, Newcastle upon Tyne, UK
²Department of Paediatric Neurology, Newcastle General Hospital, Newcastle upon Tyne, UK

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Publication History

Publication Date:
13 March 2007 (online)

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Abstract

A case of neurogenic arthrogryposis multiplex congenita (AMC) with associated neuronal migration abnormalities is described. A child with neurogenic AMC and developmental delay presented with late onset of seizures. The first trimester of the mother's pregnancy was marked by an episode of gastro-enteritis and the intrauterine death of a twin fetus. Computer tomography (CT) and magnetic resonance (MR) imaging demonstrated abnormal neuronal migration consisting of bilateral parietal polymicrogyria, and an isolated grey matter heterotopia.

Key words

Arthrogryposis - Bilateral parietal polymicrogyria - Magnetic resonance imaging - Intrauterine death - Twins