Severe Irreversible Optic Neuritis Following Mantoux Tuberculin Skin Test in a Child with Multiple Sclerosis - A Case Report

W. H. J. P. Linssen; J. J. M. Kruisdijk; F. Barkhof; L. M. E. Smit

doi:10.1055/s-2007-973728

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Neuropediatrics 1997; 28(6): 338-340
DOI: 10.1055/s-2007-973728

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Severe Irreversible Optic Neuritis Following Mantoux Tuberculin Skin Test in a Child with Multiple Sclerosis - A Case Report

W. H. J. P. Linssen¹ , J. J. M. Kruisdijk¹ , F. Barkhof² , L. M. E. Smit³

¹Department of Neurology, St Lucas Andreas Hospital, Amsterdam,
²Department of Diagnostic Radiology, Free University Hospital, Amsterdam, and
³Department of Child Neurology, Free University Hospital, Amsterdam, The Netherlands

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Publication History

Publication Date:
13 March 2007 (online)

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Abstract

A 12-year-old girl was diagnosed as suffering from multiple sclerosis. At age 14, just after recovery from an exacerbation of MS with left-sided optic neuritis, she underwent a Mantoux tuberculin skin test. Within 30 minutes she developed complete irreversible optic neuropathy of the left eye. This case illustrates the urge for caution to perform vaccinations and tuberculin skin tests not only during progressive disease activity of MS, but also in the reconvalescent phase after an acute exacerbation.

Key words

Mantoux's tuberculin skin test - Optic neuritis - Children - Multiple sclerosis