A 12-year-old girl was diagnosed as suffering from multiple sclerosis. At age 14,
just after recovery from an exacerbation of MS with left-sided optic neuritis, she
underwent a Mantoux tuberculin skin test. Within 30 minutes she developed complete
irreversible optic neuropathy of the left eye. This case illustrates the urge for
caution to perform vaccinations and tuberculin skin tests not only during progressive
disease activity of MS, but also in the reconvalescent phase after an acute exacerbation.
Mantoux's tuberculin skin test - Optic neuritis - Children - Multiple sclerosis
