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© Georg Thieme Verlag Stuttgart · New York
Effects of Strenuous Exercise on Serum Myosin Heavy Chain Fragments in Male Triathletes
09 March 2007 (online)
During the Nice Triathlon (June 26, 1994), the serum levels of type I myosin heavy chain (MHC) fragments and creatine kinase (CK and CK-MB) activities were assessed in 12 athletes in order to evaluate the exercise-induced muscle damage. Blood samples (BS) were taken 2 days before the event (baseline), on arrival, 6 and 24 h later, and 2 and 4 days later. The mean results (and SD) were respectively: MHC (μU · l-1): 142 (69), 156 (116), 242 (144), 1183 (574), 2603 (1405), 1002 (523); CK (U · l-1): 109 (27), 626 (267), 1188 (562), 1159 (442), 633 (385), 224 (119). The CK peak occurred at BS-6h for 8 subjects, and at BS-24h for the other ones. The MHC peak occurred at BS-48h in all the subjects. The CK-MB/CK ratios exhibited a profile similar to those described previously. Serum MHC peak values were correlated with CK ones (r = 0.67; p < 0.05). After a four-day recovery period, as the CK values had decreased, the MHC levels were still elevated. The main result of the study is the MHC peak occurrence at BS-48h in all the subjects.
Endurance - exercise-induced damage - skeletal muscle - myosin heavy chain - creatine kinase - recovery