Inhibition of Passive Cutaneous Anaphylaxis by Compounds of Camellia sinensis

K. Kar; P. K. Mohanta; S. P. Popli; B. N. Dhawan

doi:10.1055/s-2007-971549

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Planta Med 1981; 42(5): 75-78
DOI: 10.1055/s-2007-971549

Research Articles

Inhibition of Passive Cutaneous Anaphylaxis by Compounds of Camellia sinensis[1]

K. Kar, P. K. Mohanta, S. P. Popli, B. N. Dhawan

Central Drug Research Institute, Lucknow, India

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Publication History

Publication Date:
30 March 2007 (online)

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Abstract

Caffeine, theophylline, theobromine, (+) catechin, (-) epicatechin, gallic acid and theaflavin obtained from black tea (Camellia sinensis) inhibit passive cutaneous anaphylactic reaction in mice without affecting acetylcholine, histamine and serotonin induced broncho-constriction in the guinea pig. Theophylline and theaflavin antagonise only prostaglandin F₂ alpha induced bronchoconstriction.

Key Word Index

Camellia sinensis - Theaceae - Polyphenols - Xanthine

1 C.D.R.I. Communication No. 2752