Alkaloid Production in Catharanthus roseus Cell Cultures VIII

W. G. W. Kurz; K. B. Chatson; F. Constabel; J. P. Kutney; L. S. L. Choi; P. Kolodziejczyk; S. K. Sleigh; K. L. Stuart; B. R. Worth

doi:10.1055/s-2007-971541

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Planta Med 1981; 42(5): 22-31
DOI: 10.1055/s-2007-971541

Research Articles

Alkaloid Production in Catharanthus roseus Cell Cultures VIII[1]

Characterisation of the PRL # 200 Cell LineW. G. W. Kurz² , K. B. Chatson² , F. Constabel² , J. P. Kutney³ , L. S. L. Choi³ , P. Kolodziejczyk³ , S. K. Sleigh³ , K. L. Stuart³ , B. R. Worth³

²Prairie Regional Laboratory, National Research Council, Saskatoon, Sask, Canada
³Dept. of Chemistry, University of British Columbia VANCOUVER B.C., Canada

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Publication History

Publication Date:
30 March 2007 (online)

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Abstract

A cell line of Catharanthus roseus (L.) G. DON coded PRL # 200, was characterized with respect to its biosynthetic capabilities for indolealkaloids, in particular catharanthine, in suspension cultures. Other alkaloids isolated are vallesiachotamine isomers, ajmalicine, hörhammericine, hörhammerinine, vindolinine, 19-epivindolinine and strictosidine lactam.

Key Word Index

Catharanthus roseus - Apocynaceae - Plant Cell Cultures - Indolealkaloids - Catharanthine - Biosynthesis - Growth Parameters

1 Issued as NRCC No. 18657.