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Planta Med 1981; 43(10): 121-127
DOI: 10.1055/s-2007-971488
Research Articles

© Hippokrates Verlag Stuttgart

Struktur von Silandrin und Silymonin, zwei neuen Flavanolignanen aus einer weißblühenden Silybum marianum Varietät

Structure of Silandrin and Silymonin, two New Flavanolignans from a White Blooming Silybum marianum VarietyI. Szilági1 , P. Tétényi1 , S. Antus3 , O. Seligmann2 , V. M. Chari2 , M. Seitz2 , H. Wagner2
  • 1Institut für Arzneipflanzenforschung Budakalász
  • 2Institut für Pharmazeutische Biologie der Universität München
  • 3Forschungsgruppe für Alkaloidchemie der Ungarischen Akademie der Wissenschaften, Budapest
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Publication History

Publication Date:
30 March 2007 (online)

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Abstract

The structures of two flavanolignans, (-) silandrin and (+) silymonin, from a white flowering variety of Silybum marianum, have been elucidated as 3-desoxy-isosilybin and 3-desoxy-silydianin partly by spectroscopic investigations, partly by chemical transformation into other derivatives and their partial synthesis. In addition 5,7-dihydroxy-chromone has been isolated as a new compound.

Key Word Index

Silybum marianum - Compositae - (-)Silandrin - 3-Desoxyisosilybin - (+)Silymonin - 3-Desoxy-silydianin - Flavanolignans - 5,7-Dihydroxychromone