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Planta Med 1981; 43(9): 64-70
DOI: 10.1055/s-2007-971475
Research Articles

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Isolation of Amentoflavone from Selaginella rupestris and its Pharmacological Activity on Central Nervous System, Smooth Muscles and Isolated Frog Heart Preparations

B. K. Chakravarthy, Y. V. Rao, S. S. Gambhir, K. D. Gode
  • Department of Pharmacology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
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Publication History

Publication Date:
30 March 2007 (online)

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Abstract

Amentoflavone has been isolated from the leaves of Selaginella rupestris SPRING (Selaginellacae). This biflavonoid was tested for its activity on central nervous system, smooth muscles and isolated frog heart preparations. It was observed that amentoflavone did not have any effect on central nervous system of rats and mice, but it had antispasmodic effect on isolated guinea pig ileum.

Amentoflavone had also increased significantly the contractility of both nor-modynamic and hypodynamic frog hearts.

Key Word Index

Selaginella rupestris - Selaginellacae - Amentoflavone - Cardiac Stimulant