Planta Med 1982; 44(4): 231-233
DOI: 10.1055/s-2007-971455
Research Articles

© Hippokrates Verlag Stuttgart

Efficient Incorporation of 10-Hydroxygeraniol and 10-Hydroxynerol into Indole Alkaloids by a Cell Suspension Culture of Catharanthus roseus*

J. Balsevich, F. Constabel, W. G. W. Kurz
  • Prairie Regional Laboratory, National Research Council of Canada, Saskatoon, Saskatchewan, Canada
* Published as NRCC No. 19880
Further Information

Publication History

1981

Publication Date:
29 March 2007 (online)

Abstract

A cell suspension culture of Catharanthus roseus was evaluated with regard to its potential usage in studies of early stage indole alkaloid biosynthesis. Employing this material, 1,1,7-trideutero-10-hydroxygeraniol and 1,1,7-trideutero-10-hydroxynerol were incorporated into the alkaloids ajmalicine and strictosidine lactam in approximate proportions of 50% and 80% respectively.[2]

2 A portion of this work was presented at the 28th congress, IUPAC, Vancouver, B. C., Canada, Aug. 16-21, 1981, J. BALSEVICH, Oxygenated derivatives of geraniol and nerol.

2 A portion of this work was presented at the 28th congress, IUPAC, Vancouver, B. C., Canada, Aug. 16-21, 1981, J. BALSEVICH, Oxygenated derivatives of geraniol and nerol.