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Planta Med 1982; 44(4): 227-230
DOI: 10.1055/s-2007-971454
Research Articles

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Partial Purification and Properties of Tropine Dehydrogenase from Root Cultures of Datura stramonium

K. J. Koelen, G. G. Gross
  • Universität Ulm, Abteilung Allgemeine Botanik, FRG
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Publication History

1981

Publication Date:
29 March 2007 (online)

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Abstract

From sterile root cultures of Datura stramonium, an NADP(H)-specific tropine dehydrogenase has been isolated and characterized. The enzyme catalyzes the reversible and stereospecific oxidation of tropine and related tropane-3α-ols to the corresponding ketone. Isomeric pseudotropine (tropane-3β-ol) is neither accepted as substrate nor produced in the reverse reaction. It is assumed that this dehydrogenase is involved in the biosynthesis of tropane alkaloids.

Key Word Index

Datura stramonium - Solanaceae - Root Culture - Tropine Dehydrogenase - Tropane Alkaloids - Biosynthesis

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