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Planta Med 1982; 44(4): 207-211
DOI: 10.1055/s-2007-971448
Research Articles

© Hippokrates Verlag Stuttgart

Phthalides in the Essential Oil from Roots of Levisticum officinale*

M. J. M. Gijbels, J. J. C. Scheffer, A. Baerheim Svendsen
  • Department of Pharmacognosy, State University of Leiden, Gorlaeus Laboratories, Leiden, The Netherlands
* Dedicated to Dr. J. L. VAN EIJK on the occasion of his retirement.
Further Information

Publication History

1981

Publication Date:
29 March 2007 (online)

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Abstract

The composition of the phthalide mixture of the essential oil from roots of Levisticum officinale KOCH was investigated. The phthalide mixture was analyzed by combining separation methods - GLC, LSC and TLC - and subsequently using spectroscopic methods - IR, MS and NMR. E- and Z-butylidenephthalide, E- and Z-ligustilide, senkyunolide and validene-4,5-dihydrophthalide were found to be present; isosenkyunolide and propylidenephthalide were tentatively identified.

The influence of the isolation procedure on the composition of the phthalide mixture was tentatively studied by comparison of mixtures isolated by solvent extraction and hydrodistillation respectively.

Key Word Index

Levisticum officinale - Apiaceae (Umbelliferae) - Root - Essential Oil - Phthalides

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