Antibiotic Substances from New Zealand Plants

Rosemary F. McCallion; A. L. J. Cole; J. R. L. Walker; J. W. Blunt; M. H. G. Munro

doi:10.1055/s-2007-971422

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Planta Med 1982; 44(3): 134-138
DOI: 10.1055/s-2007-971422

Research Articles

Antibiotic Substances from New Zealand Plants

II. Polygodial, an Anti-Candida Agent from Pseudowintera colorataRosemary F. McCallion¹ , A. L. J. Cole¹ , J. R. L. Walker¹ , J. W. Blunt² , M. H. G. Munro²

¹Botany Department, University of Canterbury, Christchurch, New Zealand
²Chemistry Department, University of Canterbury, Christchurch, New Zealand

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Publication History

Publication Date:
29 March 2007 (online)

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Abstract

A bicyclic sesquiterpene dialdehyde “Polygodial” has been isolated from leaves of the New Zealand tree Pseudowintera colorata and shown to possess strong antibiotic activity against the yeast Candida albicans. Polygodial was also found in Drimys winteri but was absent from P. axillaris and P. traversii.

Key Word Index

Pseudowintera colorata - Winteraceae - Polygodial - Sesquiterpenes - Anti-Candida agent

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