Unsaturated Polyhydroxy Acids having Prostaglandin-Like Activity from Bryonia alba II. Major Components

A. G. Panossian; G. M. Avetissian; V. A. Mnatsakanian; S. G. Batrakov; S. A. Vartanian; E. S. Gabrielian; E. A. Amroyan

doi:10.1055/s-2007-969940

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Planta Med 1983; 47(1): 17-25
DOI: 10.1055/s-2007-969940

Research Articles

Unsaturated Polyhydroxy Acids having Prostaglandin-Like Activity from Bryonia alba II. Major Components

A. G. Panossian¹ , G. M. Avetissian¹ , V. A. Mnatsakanian¹ , S. G. Batrakov¹ , S. A. Vartanian¹ , E. S. Gabrielian² , E. A. Amroyan²

¹Institute of Fine Organic Chemistry, Academy of Sciences of the Armenian SSR, Yerevan, USSR
²Department of Pharmacology, Yerevan State Medical Institute, Yerevan, USSR

Further Information

Publication History

1979

Publication Date:
26 March 2007 (online)

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Abstract

The eight major components of the fraction of unsaturated polyhydroxy fatty acids, isolated from Bryonia alba L. roots, were identified as four diastereoisomeric pairs of 9,12,13-trihydroxy-trans-10, cis-15-octadecadienoic, 12,15,16-trihydroxy-cis-9, trans-13-octadecadienoic, 9,10,13-trihydroxy-trans-11, cis-15-octadecadienoic and 12,13,16-trihydroxy-cis-9, trans-14-octadecadienoic acids. Their mixture displayed prostaglandin-like activity. The possible biogenetic pathways of these compounds are discussed.

Key word Index

Bryonia alba L. - Cucurbitaceae - Prostaglandin like Activity - Polyhydroxy fatty Acids