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Planta Med 1983; 48(7): 142-144
DOI: 10.1055/s-2007-969909
Research Articles

© Hippokrates Verlag Stuttgart

Biosynthesis of Rutacridone: The N-Methylation Step

A. Baumert1 , I. N. Kuzovkina2 , M. Hieke1 , D. Gröger1
  • 1Institut für Biochemie der Pflanzen, Akademie der Wissenschaften der DDR, Halle (Saale), DDR
  • 2K. A. Timiriazev Institute of Plant Physiology, Academy of Sciences of the USSR, Moscow, USSR
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Publication History

1982

1983

Publication Date:
26 March 2007 (online)

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Abstract

The N-methylation of rutacridone was investigated. This dihydrofuroacridone derivative ist the main alkaloid in cell suspension cultures of Ruta graveolens, strain R-20. The N-methyl group is provided by L-methionine. N-methylanthranilic acid serves as excellent precursor of rutacridone. Furthermore this particular precursor could be trapped after feeding anthranilic acid in short term experiments.

Key Word Index

Ruta graveolens - Rutaceae - Tissue Culture - Rutacridone - Biosynthesis