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Planta Med 1983; 49(10): 109-114
DOI: 10.1055/s-2007-969826
Research Articles

© Hippokrates Verlag Stuttgart

Plant Antiviral Agents

IV1. Influence of Lycorine on Growth Pattern of Three Animal VirusesM. Ieven, D. A. van den Berghe, A. J. Vlietinck
  • Department of Pharmaceutical Sciences, University of Antwerp (UIA), Belgium
1 For the previous paper in this series see reference [1].
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Publication History

1983

1983

Publication Date:
26 March 2007 (online)

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Abstract

Lycorine, one of the principal alkaloids of the Amaryllidaceae, exerts an antiviral effect on several RNA and DNA viruses. This effect on the growth pattern of different viruses has now been investigated. In the presence of lycorine, a delay in virus production and a decrease in total amount of virus were observed. This inhibitory effect is concentration dependent, it is due to a block of viral protein synthesis and not to an extracellular inactivation or inhibition of viral adsorption.

Key Word Index

Clivia miniata - Amaryllidaceae - Alkaloids - Lycorine - Antiviral activity - Viral growth pattern - Poliomyelitis - Coxsackie - Herpes type 1 viruses