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Isolation and Hypoglycaemic Activity of Panaxans A, B, C, D and E, Glycans of Panax ginseng Roots11 Antidiabetes drugs, Part 1. Also Part 70 in the series on the validity of the Oriental medicines
26 February 2007 (online)
An aqueous methanol/water extract of the Oriental crude drug “ninjin” (ginseng), Panax ginseng roots from Korea, showed a remarkable hypoglycaemic activity on administration to mice. Fractionation of the extract, along with the pharmacological assays, led to isolation of five glycans, panaxans A, B, C, D and E. These constituents exhibited significant hypoglycaemic actions in normal and alloxan-induced hyperglycaemic mice.