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© Georg Thieme Verlag Stuttgart · New York
Cardiac and Extracardiac Activity of an Ethanolic Extract of Leaves of Isoplexis canariensis
26 February 2007 (online)
The paper deals with the effects of a glycosidal extract of Isoplexis canariensis (Schrophulariaceae), grown in the Canary Islands, on isolated auricle of rabbits, isolated ileum of guinea-pigs, isolated jejunum of rabbits, urinary excretion of rats and 86Rb+ uptake by red cells. The extract produced an increase in the contraction force of auricles, contractile response in guinea-pigs ileum, hypermotility followed by paralysis in the rabbit jejunum, diminution of the urinary excretion in rats and decrease of the 86Rb+ uptake by red cells. Except for the antidiuretic action, the pharmacological activity of the principles contained in the extract is similar to that of the digitalis compounds.