Planta Med 1984; 50(4): 307-309
DOI: 10.1055/s-2007-969716
Research Articles

© Georg Thieme Verlag Stuttgart · New York

Cardiac and Extracardiac Activity of an Ethanolic Extract of Leaves of Isoplexis canariensis

J. Boada1 , 2 , E. Navarro1 , R. Rodríguez1 , R. Borges1 , B. Alarcó1 , P. Martín1
  • 1Departments of Pharmacology and Biochemistry, Faculty of Medicine, University of La Laguna, Tenerife, Canary Islands
  • 2Departamento de Farmacología, Facultad de Medicina, Universidad de La Laguna, Apartado 55, La Cuesta, Tenerife, Islas Canarias, España
Further Information

Publication History



Publication Date:
26 February 2007 (online)


The paper deals with the effects of a glycosidal extract of Isoplexis canariensis (Schrophulariaceae), grown in the Canary Islands, on isolated auricle of rabbits, isolated ileum of guinea-pigs, isolated jejunum of rabbits, urinary excretion of rats and 86Rb+ uptake by red cells. The extract produced an increase in the contraction force of auricles, contractile response in guinea-pigs ileum, hypermotility followed by paralysis in the rabbit jejunum, diminution of the urinary excretion in rats and decrease of the 86Rb+ uptake by red cells. Except for the antidiuretic action, the pharmacological activity of the principles contained in the extract is similar to that of the digitalis compounds.