Antiinflammatory Activity of 3 β-Hydroxy-2,3-dihydro-withanolide F

R. D. Budhiraja; S. Sudhir; K. N. Garg

doi:10.1055/s-2007-969651

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Planta Med 1984; 50(2): 134-136
DOI: 10.1055/s-2007-969651

Research Articles

Antiinflammatory Activity of 3 β-Hydroxy-2,3-dihydro-withanolide F

R. D. Budhiraja, S. Sudhir, K. N. Garg

Department of Pharmacology, Medical College, Rohtak - 124001, Haryana, India

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Publication History

Publication Date:
26 February 2007 (online)

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Abstract

Anti-inflammatory activity of 3β-hydroxy-2,3-dihydro-withanolide F has been assessed and it was found to possess marked effects in sub-acute inflammation. A comparison of the anti-inflammatory properties showed that it is approximately 5 times more active than phenylbutazone and equally active to that of hydrocortisone on weight basis. The withanolide did not exhibit any effect on CNS.