Download PDF
Planta Med 1985; 51(4): 346-347
DOI: 10.1055/s-2007-969511
Reports

© Georg Thieme Verlag Stuttgart · New York

Plant Anticancer Agents XXXVII. Constituents of Amanoa oblongifolia [1]

Xinde Fang2 , N. P. Dhammika Nanayakkara3 , Charles H. Phoebe4  Jr. , John M. Pezzuto3 , A. Douglas Kinghorn3 , Norman R. Farnsworth3
  • 2A Visiting Scholar in the World Health Organization Collaborating Centre for Traditional Medicine, College of Pharmacy, University of Illinois at Chicago, on leave from the Shanghai College of Traditional Chinese Medicine, Shanghai, People's Republic of China
  • 3Program for Collaborative Research in the Pharmaceutical Sciences and Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, Health Sciences Center, University of Illinois at Chicago, Chicago, Illinois 60612, U.S.A.
  • 4Life Sciences Laboratory, Water's Associates, Milford, Massachusetts 07157, U.S.A.
Further Information

Publication History

1985

1985

Publication Date:
26 February 2007 (online)

  PDF Download  Permissions and Reprints

Abstract

4′-Demethyldeoxypodophyllotoxin was isolated as the sole cytotoxic constituent of a chloroform-soluble extract of the stem bark of Amanoa oblongifolia. Also identified from this extract were a number of noncytotoxic isolates that comprised the lignans, (+)-sesamin and paulownin, the triterpenes, friedelin, canophyllol, betulin, betulinic acid, and ursolic acid, and the sterols, β-sitosterol and daucosterol.

1 For the previous paper in this series, see reference 1

1 For the previous paper in this series, see reference 1

      >