Planta Med 1985; 51(3): 215-217
DOI: 10.1055/s-2007-969460
Research Articles

© Georg Thieme Verlag Stuttgart · New York

Coumarins from Polygala paniculata

M. Hamburger1 , M. Gupta2 , K. Hostettmann1
  • 1Institut de Pharmacognosie et Phytochimie, Ecole de Pharmacie, Université de Lausanne, 2, rue Vuillermet, CH-1005 Lausanne, Switzerland
  • 2Laboratorio Especializado de Analisis, Facultad de Ciencias Naturalis y Farmacia, Universidad de Panama, Panama, Republic of Panama
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26. Februar 2007 (online)


From the petrol ether and chloroform extracts of Polygala paniculata L. (Polygalaceae), possessing both molluscicidal and antifungal properties, four coumarins were isolated by flash chromatography and centrifugal thin-layer chromatography. They were identified as aurapten, phebalosin, murrangatin and 7-methoxy-8-(l,4-dihydroxy-3-methyl-2-butenyl)coumarin, a new natural product. Among these compounds phebalosin showed biological activity, but proved to be very unstable in aqueous solution.