Coumarins from Polygala paniculata

M. Hamburger; M. Gupta; K. Hostettmann

doi:10.1055/s-2007-969460

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Planta Med 1985; 51(3): 215-217
DOI: 10.1055/s-2007-969460

Research Articles

Coumarins from Polygala paniculata

M. Hamburger¹ , M. Gupta² , K. Hostettmann¹

¹Institut de Pharmacognosie et Phytochimie, Ecole de Pharmacie, Université de Lausanne, 2, rue Vuillermet, CH-1005 Lausanne, Switzerland
²Laboratorio Especializado de Analisis, Facultad de Ciencias Naturalis y Farmacia, Universidad de Panama, Panama, Republic of Panama

Further Information

Publication History

1984

1985

Publication Date:
26 February 2007 (online)

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Abstract

From the petrol ether and chloroform extracts of Polygala paniculata L. (Polygalaceae), possessing both molluscicidal and antifungal properties, four coumarins were isolated by flash chromatography and centrifugal thin-layer chromatography. They were identified as aurapten, phebalosin, murrangatin and 7-methoxy-8-(l,4-dihydroxy-3-methyl-2-butenyl)coumarin, a new natural product. Among these compounds phebalosin showed biological activity, but proved to be very unstable in aqueous solution.

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