Isolation and Hypoglycemic Activity of Lithospermans A, B and C, Glycans of Lithospermum erythrorhizon Roots1

Chohachi Konno; Takakazu Mizuno; Hiroshi Hikino

doi:10.1055/s-2007-969434

Planta Medica, Inhaltsverzeichnis

Planta Med 1985; 51(2): 157-158
DOI: 10.1055/s-2007-969434

Reports

Isolation and Hypoglycemic Activity of Lithospermans A, B and C, Glycans of Lithospermum erythrorhizon Roots¹

Chohachi Konno, Takakazu Mizuno, Hiroshi Hikino

Pharmaceutical Institute, Tohoku University, Aoba-yama, Sendai, Japan

1 Antidiabetes drugs, Part 3. Also Part 79 in the validity of the Oriental medicines

Abstract

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Abstract

A water extract of the Oriental crude drug “shikon”, Lithospermum erythrorhizon roots, remarkably diminished the plasma sugar level in mice. Fractionation of the extract by monitoring the activity yielded three glycans, lithospermans A, B and C. These glycans exerted marked hypoglycemic effects in normal and alloxan-induced hyperglycemic mice.

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