© Georg Thieme Verlag Stuttgart · New York
Plants as Sources of Antimalarial Drugs. Part 31 Eurycoma longifolia1 For parts 1 and 2 see references (5) and (6).
26 February 2007 (online)
Extracts of Eurycoma longifolia Jack (Simaroubaceae) have been tested for antiplasmodial activity against a multi-drug resistant Thailand strain (K-1) of Plasmodium falciparum in vitro. 10-Hydroxycanthin-6-one, eurycomalactone, eurycomanone and eurycomanol were isolated form the plant. The in vitro antimalarial activities of these compounds are reported together with that of 6-hydroxy-5, 6-dehydroeurycomalactone.