Planta Med 1986; 52(2): 80-83
DOI: 10.1055/s-2007-969084
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© Georg Thieme Verlag Stuttgart · New York

Cussonosides A and B, two Triterpene-saponins from Cussonia barteri

M. A. Dubois1 , M. Ilyas2 , H. Wagner3
  • 1Laboratoire de Pharmacognosie, Faculté de Pharmacie, 7, Bd. Jeanne D'Arc, F-21033 Dijon Cedex, France
  • 2Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria, Nigeria
  • 3Institut für Pharmazeutische Biologie der Universität München, Karlstr. 29, D-8000 München 2, Federal Republic of Germany
Further Information

Publication History

9 9 1985

Publication Date:
26 February 2007 (online)


Two major saponins have been isolated from the stem bark of Cussonia barteri Seem (Araliaceae). Structural elucidation employing mainly 1H- and 13C-NMR, FAB-MS and GC-MS spectroscopic methods revealed a new hederagenin 28-O-[α-L-rhamnopyranosyl (1 → 4)-β-D-glucopyranosyl (1 → 6)]-β-D-glucopyranosyl ester (Cussonoside A), and the corresponding oleanolic acid analogue (Cussonoside B). Cussonoside A exhibits a pronounced sedative effect.