Abstract
A detailed phytochemical investigation of an extract of Bacopa monniera resulted in the isolation of two new dammarane glycosides along with eight known
compounds. They have been identified as glycosides of the 20-deoxy derivatives of
jujubogenin and pseudojujubogenin. The structures were established by different spectroscopic
methods that included 1D and 2D NMR experiments. The compounds were tested for their
cytotoxicity, antileishmanial, antimalarial, antioxidant, and anti-inflammatory activities.
Only few compounds exhibited mild to moderate cytotoxicity towards non-cancerous kidney
cell lines.
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Ikhlas A. Khan
National Center for Natural Products Research
University of Mississippi
University
MS 38677
USA
Telefon: +1-662-915-7821
Fax: +1-662-915-7989
eMail: ikhan@olemiss.edu
