Endoscopy 2007; 39: E261
DOI: 10.1055/s-2007-966552
Unusual cases and technical notes

© Georg Thieme Verlag KG Stuttgart · New York

Pyogenic liver abscess as a complication of sigmoid polypectomy

A.  D.  Farmer1 , K.  Browett1 , V.  Rusius1 , S.  Bhalerao2 , M.  R.  Anderson1
  • 1Department of Gastroenterology, City Hospital, Birmingham, United Kingdom
  • 2Department of Surgery, City Hospital, Birmingham, United Kingdom
Further Information

Publication History

Publication Date:
24 October 2007 (online)

A previously well 65-year-old man underwent a routine colonoscopy after being referred with diarrhea. A 15-mm pedunculated polyp was observed at the rectosigmoid junction and an uncomplicated polypectomy was performed; examination to the cecum was otherwise normal. He was discharged 3 hours after this procedure. Histological examination of the polyp revealed a tubulovillous adenoma with low-grade dysplasia. The patient returned 3 days later with fevers and rigors, but with no abdominal pain. The symptoms had begun 12 hours after the colonoscopy, and on admission he was found to be hypotensive and septic, with a low-grade fever. Clinical examination was unremarkable. He had a neutrophil leukocytosis of 43.6 × 109/L and a C-reactive protein level of 218 mg/L, but liver function tests were normal. Blood cultures grew Streptococcus milleri, and appropriate antibiotic therapy was commenced. Despite this treatment, however, he continued to show signs of sepsis. Abdominal computed tomography 6 days after his colonoscopy demonstrated a multiloculated, right-lobe liver abscess ([Fig. 1]), and 300 mL of purulent fluid was aspirated from this, which also grew S. milleri. After drainage of this abscess he made an uncomplicated recovery.

Fig. 1 Computed tomographic view (coronal reconstruction) showing the pyogenic liver abscess in the right lobe of the liver.

We believe that he developed the pyogenic liver abscess after the polypectomy. The likely pathophysiological mechanism was the development of a pylephlebitis following the polypectomy, with subsequent seeding to the liver. The abdominal computed tomographic scan was performed 6 days after the polypectomy, which was enough time for a large abscess to form. Pylephlebitis is a recognized complication of intra-abdominal infection and colonic perforation [1]. Indeed, pyogenic liver abscesses have been described as a presenting feature of colonic tubulovillous adenoma [2]. S. milleri is a common cause of liver abscess and this has been described as a complication following the colonscopic removal of an impacted fish bone [3]. We believe this to be first case report of a S. milleri liver abscess complicating polypectomy of a tubulovillous adenoma in the sigmoid colon.



A. D. Farmer

Department of Gastroenterology

Sandwell and West Birmingham NHS Trust

City Hospital

Dudley Road

Birmingham B18 7QH

United Kingdom

Fax: +44-1785253672

Email: penv@mac.com