Int J Sports Med 1988; 09(4): 284-288
DOI: 10.1055/s-2007-1025023
© Georg Thieme Verlag Stuttgart · New York

Blood Lactate During Exercise: Time Course of Training Adaptation in Humans

G. A. Gaesser, D. C. Poole
  • Department of Kinesiology, University of California, Los Angeles, Los Angeles, California
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14. März 2008 (online)


We determined the time course of adaptation in blood lactate concentration ([La]) during constant-load exercise in response to training. Thirteen healthy subjects (11 males, 2 females) exercised on a cycle ergometer for 30 min/day at a work rate calculated to elicit 70% of pre-training V̇O2max, 6 days/week for 3 weeks. V̇O2max and blood [La] during constant-load exercise (training work rate) were determined at the end of each week of training. Training increased V̇O2max 8.5% (from 48.2±1.5 ml·kg-1·min-1 pre-training to 52.3±1.4 ml·kg-1·min-1 post-training, P < 0.01) and decreased constand-load blood [La] 53% (from 7.8 + 0.6 mM pre-training to 3.7±0.3 mM post-training, P < 0.01). The training-induced reduction in exercise blood [La] was well fit to an exponential (5.5 e (-t/22) + 2.3, r = 0.99) with a half-time of 10.7 days. However, this was not the case for the time course of V̇O2max adaptation. The absolute decrease in blood [La] was correlated with the initial blood [La] (r = 0.88, P < 0.01), but changes in V̇O2max were not significantly correlated with initial blood [La] (r = -0.14) nor with changes in blood [La] (r = -0.02). We conclude that (1) blood [La] response to constant-load exercise decreases rapidly and exponentially with training, with a t1/2 of 10.7 days, (2) the magnitude of training adaptation is positively related to the initial blood [La], and (3) the time course and extent of the training-induced adaptations of blood [La] and V̇O2max appear to be independent of one another.