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Int J Sports Med 1994; 15: S116-S121
DOI: 10.1055/s-2007-1021125
DOI: 10.1055/s-2007-1021125
The Immune System during Exposure to Extreme Physiologic Conditions
Further Information
Publication History
Publication Date:
14 March 2008 (online)
Abstract
It is not clear how the immune system is modulated in response to physical stress (e.g. trauma, surgery, burn and sepsis). In order to better understand the stress-induced immune changes, effects of isolated Stressors are evaluated. Human experiments include hypoxia, head-up tilt, hyperthermina and exercise, which influence all lymphocyte subtypes and especially so the natural killer (NK) cells. In essence, the immune response is enhanced even by light physical stress, but suppressed after prolonged, intense stress.
Key words
Aerospace medicine - adrenaline - β-endorphine - cytokine - exercise - hyperthermia - hypoxia - growth hormone - lymphocyte - lymphokine activated killer cell - natural killer cell - sport.