The application of phrenic nerve pacing is an effective method of respiratory support
in adults with certain forms of acquired failure of automatic ventilation. The experience
with one infant suffering from congenital central hypoventilation (Ondine's syndrome) is summarized in this report. Stimulation electrodes were implanted on
the thoracic portion of each phrenic nerve. After a cumbersome period of intensive
medical care and conditioning of the phrenic nerve-diaphragm system, the patient could
be weaned off the respirator. Severe upper airway obstruction, however, required tracheostomy.
Bilateral simultaneous pacing has been effectíve now for more than 2 years providing
the desired normal ventilation during sleep. The state of the art of phrenic nerve
pacing is described.
Ondine's syndrome - Phrenic nerve pacing
