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Horm Metab Res 1981; 13(11): 609-611
DOI: 10.1055/s-2007-1019351
© Georg Thieme Verlag, Stuttgart · New York

An Early Effect of Cortisol, Previous to its Glycogenogenic Action

M. Egaña, M. J. Sancho, J. M. Macarulla
  • Departamento de Bioquimica, Facultad de Ciencias, Universidad del Pais Vasco, Bilbao, Spain
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Publication History

1981

1981

Publication Date:
14 March 2008 (online)

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Summary

Cortisol produces a glycogenogenic effect 5 hours after intraperitoneal injection to 3 day old chicks. This effect is dependent on protein synthesis because it can be blocked by antibiotics such as actinomycin D. On the other hand, there is a previous glycogenolytic effect 45 minutes after cortisol administration which is independent of protein synthesis. Thyroid hormones produce a similar early effect as has been previously shown. However, the observed glycogenolysis after cortisol injection is not correlated with an enhancement in the liver cAMP levels.

Key-Words:

Cortisol - Glycogenogenesis - Glycogenolysis