Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000025.xml
Horm Metab Res 1981; 13(1): 60-61
DOI: 10.1055/s-2007-1019170
DOI: 10.1055/s-2007-1019170
Short Communications
© Georg Thieme Verlag, Stuttgart · New York
Effect of Leucine on GSH Levels of Rat Pancreatic Islets
Further Information
Publication History
1979
1980
Publication Date:
14 March 2008 (online)
Summary
GSH levels were determined in rat pancreatic islets after incubation of batches of 5 islets in 1 ml medium for 90 min in the absence or presence of glucose (5.6 mM) with and without addition of leucine (10 mM). In the presence of glucose, but not in its absence, leucine significantly elevated the islet content of GSH.
It is suggested that this increase is due to the rise of the NADPH/NADP ratio induced by leucine and that insulin secretion triggered by leucine may at least in part be related to its effect on GSH.