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Endoscopy 1983; 15(1): 16-20
DOI: 10.1055/s-2007-1018598
© Georg Thieme Verlag KG Stuttgart · New York

The Malignant Potential of Colorectal Polyps - A New Statistical Approach -

P. Hermanek, P. Frühmorgen, I. Guggenmoos-Holzmann, A. Altendorf, W. Matek
  • Department of Surgical Pathology (Head: Prof. P. Hermanek, M.D.)
  • Medical Department (Director: Prof. L. Demling, M.D.)
  • Surgical Department (Director: Prof. F.P. Gall, M.D.)
  • The Institute for Medical Statistics and Documentation (Head: Prof. L. Horbach, M.D.) of the University of Erlangen-Nuremberg
Supported by the Deutsche Forschungsgemeinschaft (SFB 118)
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Publication History

Publication Date:
17 March 2008 (online)

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Summary

To investigate the factors influencing the malignant potential of adenomas, a logit analysis was carried out. The malignancy rate (frequency of malignant areas infiltrating into submucosa) in adenomas is influenced by

1. the size of the adenoma,

2. the interrelationship between size and histological type (tubular, tubulo-villous, villous) and

3. the macroscopic growth pattern (pedunculated, semipedunculated, sessile).

No influence is exercised by the number of adenomas, their localization, or the sex of the patient.

Key words:

Adenoma - Adenoma-carcinoma sequence - Colorectal adenoma - Colorectal carcinoma