Seminars in Reproductive Endocrinology, Inhaltsverzeichnis Semin Reprod Med 1998; 16(2): 135-143DOI: 10.1055/s-2007-1016264 Copyright © 1998 by Thieme Medical Publishers, Inc.Androgen Effects on the Central Nervous System in the Postmenopausal WomanLeo Plouffe* Jr. , James A. Simon† *Section of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Medical College of Georgia, Augusta, Georgia; and Senior Clinical Research Physician, Eli Lilly and Company, Indianapolis, Indianapolis; and †Women's Health Research Center, Laurel, Maryland Artikel empfehlen Abstract als PDF herunterladen Artikel einzeln kaufen Abstract Interest in the effects of androgens on the central nervous system (CNS) in postmenopausal women dates back to at least fifty years. The mechansisms of action of androgens on the CNS are extremely complex and multi-faceted. Much data has been accumulated in recent years that suggest a beneficial role of androgens in several aspects of CNS function. These include positive effects on mood, cognition, memory, and libido. The information continues to be preliminary in nature and requires further investigations. There is evidence of altered androgen metabolism triggered by exogenous postmenopausal estrogen therapy. While promising, the current body of evidence does not yet support the routine addition of androgens to postmenopausal hormone therapy. Keywords: Central nervous system - menopause - testosterone - methyltestosterone - libido PDF (1907 kb)
