Summary
The effect of histamine on parathyroid function was studied in two patients. 2.75
mg histamine phosphate administered intravenously over 120 minutes induced the well
known clinical effects such as facial flushing, fall in blood pressure and increase
in heart rate. But the serum calcium concentration, serum immunoreactive parathormone
concentration, urinary excretion of cAMP and tubular phosphate reabsorption did not
change significantly. It is concluded that stimulation of histamine receptors does
not play an important role in the regulation of parathyroid activity.
Key-Words:
