Cyclic Nucleotides in Ascites from Ovarian Carcinoma

A. Francavilla; R. Sabatini; E. Ierardi; A. Amoruso; C. Panella; L. Polimeno; A. Restaino; L. Selvaggi

doi:10.1055/s-2007-1013624

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Horm Metab Res 1985; 17(11): 617-618
DOI: 10.1055/s-2007-1013624

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Cyclic Nucleotides in Ascites from Ovarian Carcinoma

A. Francavilla¹ , R. Sabatini² , E. Ierardi¹ , A. Amoruso¹ , C. Panella¹ , L. Polimeno¹ , A. Restaino² , L. Selvaggi²

¹Cattedra di Malattie dell'Apparato Digerente, Università di Bari, Bari, Italy
²1^ Clinica Ostetrica e Ginecologica, Università di Bari, Bari, Italy

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Publication History

1985

1985

Publication Date:
14 March 2008 (online)

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Summary

Cyclic Adenosine monophosphate (cAMP) and cyclic Guanosine monophosphate (cGMP) were assayed in ascitic fluid from 27 patients with ovarian carcinoma and 23 patients with liver cirrhosis. The value of these cyclic nucleotides was correlated with standard methods for the clinical evaluation of tumors. No change in the cGMP levels was found in either of these groups. The cAMP content, however, was increased in 23 of the 27 cases of ovarian carcinoma. The high cAMP level was correlated with the cytological findings in only 13 (48.1%) of these cases.