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Horm Metab Res 1985; 17(10): 507-509
DOI: 10.1055/s-2007-1013590
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© Georg Thieme Verlag, Stuttgart · New York

Effect of Sex and Age on Serum Aldosterone and Thyroid Hormones in the Laboratory Rat

F. Tang
  • Department of Physiology, Faculty of Medicine, University of Hong Kong, Hong Kong
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Publication History

1983

1984

Publication Date:
14 March 2008 (online)

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Summary

Serum levels of aldosterone, tri-iodo thyronine (T3) and thyroxine (T4) were measured in male and female rats aged 3 months, 12 months, and 18 months. Female rats were found to have higher aldosterone and T3 levels, and lower T4 level than the male. No age-related change was observed in serum aldosterone in either sex. In contrast, serum T4 were found to decrease with age in both sexes while serum T3 showed an age-associated diminution in the male only. Serum testosterone was also measured in the male rats and was found to decline with age.

Key-Words:

Sex - Age - Serum aldosterone - T3 - T4 - Testosterone - Rat