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Horm Metab Res 1985; 17(5): 244-246
DOI: 10.1055/s-2007-1013505
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© Georg Thieme Verlag, Stuttgart · New York

The Urinary Excretion of Ionized and Non-Ionized Calcium by Rats Treated with 1.25-Dihydroxycholecalciferol

R. C. Puche, D. A. Caferra, M. C. Fernandez, M. E. Locatto
  • Departamento de Ciencias Fisiológicas, Facultad de Medicina, Santa Fé, Rosario, República Argentina
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Publication History

1983

1983

Publication Date:
14 March 2008 (online)

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Summary

The administration of 1,25-dihydroxycholecalciferol to rats increased their calciuresis as a power function of the dose. Up to 95% of the urinary calcium was excreted as a non-ionized complex, together with equimolar amounts of citrate. The stoichiometry between calcium and citrate, observed at all dose levels, suggests that citrate metabolism is coordinated with the mobilization of calcium.

Key-Words:

Vitamin D - 1,25-Dihydroxycholecalciferol - Calcium - Calciuria - Ionized Calcium