Using the forearm technique, muscle substrate balances were measured in healthy volunteers
under the influence of a low dose intraarterial infusion of β-hydroxybutyrate. The
ketone body led to a prompt cessation of muscular release of glycerol and free fatty
acids, indicating inhibited muscular triglyceride lipolysis. This finding confirms
the concept of substrate regulation of muscle triglyceride lipolysis in vivo.
Human Forearm
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Substrate Metabolism
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Muscle Metabolism
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Lipolysis
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Ketone Bodies