Horm Metab Res 1986; 18(7): 473-475
DOI: 10.1055/s-2007-1012349

© Georg Thieme Verlag, Stuttgart · New York

Cephalic Phase of Insulin Secretion in Obese Women

J. I. Osuna, I. Pages, M. A. Motiño, E. Rodriguez, C. Osorio
  • Department of Physiology and Biochemistry, Faculty of Medicine, University of Granada, Granada, Spain
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Publication History



Publication Date:
14 March 2008 (online)


The cephalic phase of reflex insulin secretion was studied in normoglycemic and normoinsulinemic female patients, obese (more than 30% over IBW) and normal subjects.

After an overnight fasting, at the sight of breakfast food, the obese group did not present a cephalic response. Their glycemia and insulinemia levels remained at base levels.

One minute after visual and olfactory stimulation, a statistically significant rise in immunoreactive insulin levels which was maintained throughout the test, was observed in the control group.