Insulin resistance was assessed by Insulin Tolerance Test (ITT) in 12 patients with
FCPD, 10 with NIDDM and 12 age and sex matched control subjects. The mean BMI of the
FCPD was lower than the NIDDM and control groups (P < 0.001). There was no significant
difference between the mean fasting plasma glucose or HbA1 between the FCPD and NIDDM
patients. The mean fasting C-peptide of the FCPD group was significantly lower than
the NIDDM and control groups (P < 0.001). The mean glucose disposal rate (KITT) was 5.57±2.28 in the control group, 2.15±2.00 in the FCPD and 1.77+0.91 in the NIDDM
group (P < 0.001, control vs FCPD and NIDDM). The difference in KITT between FCPD and NIDDM groups was not significant statistically. The data suggests
that patients with FCPD have evidence of insulin resistance and this is similar to
that seen in NIDDM patients.
MRDM
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FCPD
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Tropical Diabetes
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Chronic Pancreatitis
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Insulin Resistance
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Fibrocalculous Pancreatic Diabetes
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Insulin Tolerance Test
