Summary
In 78 patients with high-risk bleeding peptic ulcers (either with active bleeding
or non-bleeding visible vessel) endoscopic hemostasis by injection of adrenaline and
polidocanol was attempted. Sclerotherapy was performed in 70 (90 %) patients. Initial
hemostasis was achieved in 35 (94.5 %) patients with active bleeding, and permanent
hemostasis in 61 (87 %). Efficacy of injection therapy was significantly lower in
ulcers larger than 2 cm (p = 0.001), and in those located on the posteroinferior duodenal
wall (p = 0.03). It was not possible to perform endoscopic injection in 8 (10 %) patients
due to difficulty of access, lesions located mainly high on the lesser gastric curvature
and on the posteroinferior duodenal wall. From these results we conclude that endoscopic
injection is a very useful technique for the initial treatment of high-risk bleeding
peptic ulcer, although the size and anatomical location of the lesions may be a limitation
of its use.
Key words:
Endoscopicinjection - Size - Location - High-risk bleeding peptic ulcer
