Abstract
A 59-year-old woman with advanced gastric cancer was treated with continuous 5-fluorouracil
infusion for thirty-five days. Endoscopy of the upper gastrointestinal tract was performed
due to continuing nausea seven days after the cessation of 5-fluorouracil infusion
and revealed multiple erosions in the antrum which were absent before chemotherapy.
Continuous 5-fluorouracil infusion was probably the cause of acute gastric mucosal
lesions and should be included in the differential diagnosis of dyspepsia in 5-FU-treated
patients.