Freshly isolated rat hepatocytes incubated in a medium containing bovine serum albumin
partially purified by charcoal treatment at pH 3 are three times more responsive to
insulin with regard to α-aminoisobutyric acid uptake than those incubated in medium
containing regular bovine serum albumin. This finding should facilitate future work
in isolated hepatocytes, a cell system that for the most part has been considered
relatively unresponsive to insulin.
Insulin - Hepatocytes - Insulin Action - Fatty Acid-free Albumin - Bovine Serum Albumin