The aim of the present study was the observation of the frequency of antithyroid autoantibodies
in the population in low endemic goitre area after mass iodine prophylaxis after the
Chernobyl catastrophe and the estimation of TSH and thyroid hormones secretion in
this population. On the basis of the investigations carried out we could conclude
that the frequency of antithyroid autoantibodies in the population with confirmed
endemic goitre is comparable to the frequency of antithyroid autoantibodies in the
healthy population. ATA occurrence in children after iodine prophylaxis could confirm
the hypothesis that thyroglobulin immunity is higher after iodine intake. The lower
T3 concentration observed in the group with antithyroid autoantibodies suggests that
autoantibodies may be involved in the thyroid hormones synthesis or peripheral conversion
of thyroid hormones.
Antithyroid Autoantibodies - Chernobyl Catastrophe - Iodine Prophylaxis - Endemic
Goitre
