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Horm Metab Res 1992; 24(11): 504-507
DOI: 10.1055/s-2007-1003375
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© Georg Thieme Verlag, Stuttgart · New York

Influence of Paracetamol, Sulfanilamide and Ascorbic Acid on the Electrocatalytic Glucose Sensor

S. Saeger1 , W. Preidel2 , L. Ruprecht3
  • 1Institut für Physiologie und Biokybernetik, Universität Erlangen, Erlangen
  • 2Zentralabteilung Forschung und Entwicklung, Siemens AG, Erlangen
  • 3Forschungsinstitut für Umwelt und Gesundheit (GSF), München, Germany
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Publication History

1990

1992

Publication Date:
14 March 2008 (online)

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Summary

An electrocatalytic glucose sensor for in vivo application has been developed. The principle of measurement is based on the direct electrochemical oxidation of glucose at a platinum electrode without an enzymatic reaction.

In an in vivo experiment with sheep the glucose sensor was tested with respect to its cross-sensitivity towards ascorbic acid, paracetamol and sulfanilamide. The influence of these substances could be reduced by an adapted calibration to such an extent, that the sensor performance could be ensured.

Key words

Electrocatalytic Glucose Sensor - In-Vivo-Measurement - Cross-Sensitivity - Drugs - Sensor Performance