The Effect of Hyperosmolarity on Muscle Glycogen Accumulation

J. Li; Julie S. Stillman; J. N. Clore; W. G. Blackard

doi:10.1055/s-2007-1003267

Hormone and Metabolic Research, Inhaltsverzeichnis

Horm Metab Res 1992; 24(3): 99-102
DOI: 10.1055/s-2007-1003267

Originals Basic

The Effect of Hyperosmolarity on Muscle Glycogen Accumulation

J. Li² , Julie S. Stillman¹ , J. N. Clore¹ , W. G. Blackard¹

¹Department of Medicine, Medical College of Virginia, Richmond, Virginia, U. S. A.
²Department of Medicine, West China University of Medical Sciences, Chengdu, P. R. China

Abstract

als PDF herunterladen

Summary

Soleus (red) and extensor digitorum longus (white) muscles from Sprague Dawley rats were incubated with 6-¹⁴C-labelled glucose in normal and in hyperosmotic media. Hyperosmolarity decreased 6-¹⁴C-glucose incorporation into muscle glycogen in a dose dependent manner and increased glycolysis and glucose oxidation. Increased glycogenolysis rather than decreased glycogenesis was responsible for the reduction in labelled glycogen accumulation.

Key words

Glycogen - Osmolarity - Muscle

PDF (423 kb)