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Horm Metab Res 1992; 24(1): 31-33
DOI: 10.1055/s-2007-1003246
Clinical

© Georg Thieme Verlag, Stuttgart · New York

Effect of LHRH on Plasma 7B2 in Patients with Gonadotropin-Producing Pituitary Adenomas

H. Iguchi1 , Reiko Demura3 , D. Yasuda2 , H. Wakasugi2
  • 1Department of Biochemistry, National Kyusu Cancer Center, Fukuoka, Japan
  • 2Department of Gastroenterology, National Kyusu Cancer Center, Fukuoka, Japan
  • 3Department of Internal Medicine, Tokyo Women's Medical College, Tokyo, Japan
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Publikationsverlauf

1990

1991

Publikationsdatum:
14. März 2008 (online)

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Summary

Plasma immunoreactive (IR)-7B2 was measured in four patients with gonadotropin-producing pituitary adenomas. The basal level of plasma IR-7B2 was elevated in one of the four patients. Hyperresponse of plasma IR-7B2 to LHRH or LHRH/TRH was noted in two patients tested. 7B2 was positively stained in a paraffin-embedded section of gonadotropin-producing pituitary adenoma obtained at surgery. These findings suggest that 7B2 is produced in gonadotropin-producing pituitary adenomas and secreted into the blood stream under certain conditions. 7B2 may be a useful marker for gonadotropin-producing pituitary adenomas.

Key words

7B2 - Pituitary Adenoma - LHRH