Lactate Dehydrogenase Isozymes in Uterine Fluid of Infertile Women

Summary

Electrophoretic studies revealed predominance of LDH isozymes (LDH⁴ and LDH⁵: M-isozymes) throughout the menstrual cycle in the uterine luminal fluid of both parous and infertile women. Parous women M-isozymes maintain higher activity during phase I to phase III (early follicular phase to ovulatory phase) than infertile women. During the post-ovulatory phase (phase IV) the M-isozyme shows lowest level in parous women. In contrast, during this phase (phase IV) to late-luteal phase (phase VI) the M-isozymes show high activity in the fluid milieu of infertile women.

Isozymes - Uterine Fluid - Infertile Women